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Semi-mechanistic Population Pharmacokinetic Modeling of DZIF-10c, a Neutralizing Antibody Against SARS-Cov-2: Predicting Systemic and Lung Exposure Following Inhaled and Intravenous Administration

Sree Kurup, Nieves Velez de Mendizabal,Stephan Becker, Erica Bolella, Dorothy De Sousa,Gerd Fätkenheuer,Henning Gruell,Florian Klein,Jakob J Malin,Ulrike Schmid,Julia Korell

Journal of Pharmacokinetics and Pharmacodynamics（2024）

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Key words
Monoclonal antibodies,Population pharmacokinetics,Pharmacokinetic model,Semi-mechanistic,Allometric scaling,Inhaled administration
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