Combined Loss of Glyoxalase 1 and Aldehyde Dehydrogenase 3a1 Amplifies Dicarbonyl Stress, Impairs Proteasome Activity Resulting in Hyperglycemia and Activated Retinal Angiogenesis
Metabolism(2025)
Key words
GLO1,ALDH3A1,MG-derived hydroimidazolone 1 (MG-H1),Dicarbonyl stress,Proteasome dysfunction,Diabetes,Diabetic retinopathy,Zebrafish
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