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IDH-mutant Astrocytomas with Primitive Neuronal Component Have a Distinct Methylation Profile and a Higher Risk of Leptomeningeal Spread.

Felix Hinz,Dennis Friedel,Andrey Korshunov, Franziska M. Ippen, Henri Bogumil,Rouzbeh Banan,Sebastian Brandner,Martin Hasselblatt,Henning B. Boldt, Vaidas Dirse,Hildegard Dohmen,Eleonora Aronica,Michael Brodhun,Marike L. D. Broekman, David Capper,Asan Cherkezov,Maximilian Y. Deng,Vera van Dis,Jörg Felsberg,Stephan Frank,Pim J. French, Rüdiger Gerlach,Kirsten Göbel,Eric Goold,Jürgen Hench, Sven Kantelhardt,Patricia Kohlhof-Meinecke,Sandro Krieg,Christian Mawrin,Gillian Morrison,Angelika Mühlebner,Koray Ozduman, Stefan M. Pfister, Pietro Luigi Poliani,Marco Prinz,Guido Reifenberger,Markus J. Riemenschneider,Roman Sankowski,Daniel Schrimpf,Martin Sill,Matija Snuderl,Robert M. Verdijk, Mathew R. Voisin,Pieter Wesseling,Wolfgang Wick,David E. Reuss,Andreas von Deimling,Felix Sahm,Sybren L. N. Maas,Abigail K. Suwala

Acta Neuropathologica（2025）

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关键词
Astrocytoma,IDH-mutant,Primitive neuronal component,DNA methylation,RB1,MYCN
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