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The Phenylalanine-and-glycine Repeats of NUP98 Oncofusions Form Condensates That Selectively Partition Transcriptional Coactivators

Jeong Hyun Ahn,Yiran Guo, Heankel Lyons,Samuel G. Mackintosh, Benjamin K. Lau,Ricky D. Edmondson,Stephanie D. Byrum, Aaron J. Storey,Alan J. Tackett, Ling Cai,Benjamin R. Sabari,Gang Greg Wang

Molecular Cell(2025)

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Key words
phase separation,NUP98,fusion protein,biomolecular condensate,selective partitioning,transcriptional regulation,leukemia,MLL,WDR5,coactivator
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