Design, Synthesis, and Computational Evaluation of 3,4-Dihydroquinolin-2(1h)-one Analogues As Potential VEGFR2 Inhibitors in Glioblastoma Multiforme

Shafeek Buhlak, Nadeem Abad, Jihane Akachar, Sana Saffour, Yunus Kesgun, Sevval Dik, Betul Yasin, Gizem Bati-Ayaz, Essam Hanashalshahaby,Hasan Türkez,Adil Mardinoglu

Pharmaceuticals（2025）

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glioblastoma multiforme,3,4-dihydroquinolin-2(,)-one,therapeutic efficacy,molecular docking,molecular dynamics,VEGFA–VEGFR2 pathway,anti-cancer

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