NPRL2 Gene Therapy Induces Effective Antitumor Immunity in KRAS/STK11 Mutant Anti-Pd1 Resistant Metastatic Non-Small Cell Lung Cancer (NSCLC) in a Humanized Mouse Model

Ismail M Meraz, Mourad Majidi, Renduo Song,Feng Meng, Lihui Gao,Qi Wang,Jing Wang, Elizabeth J Shpall,Jack A Roth

eLife（2025）

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nprl2 gene therapy,NSCLC,anti-PD1 resistance,KRAS/STK11 mutation,humanized mouse model

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