Adaptative Divergence of Cryptococcus Neoformans: Phenetic and Metabolomic Profiles Reveal Distinct Pathways of Virulence and Resistance in Clinical Vs. Environmental Isolates

Camila Botelho Miguel, Geovana Pina Vilela, Lara Mamede Almeida, Mariane Andrade Moreira, Glicélia Pereira Silva, Jamil Miguel-Neto, Melissa Carvalho Martins-de-Abreu, Ferdinando Agostinho,Javier Emilio Lazo-Chica, Mariana Santos Cardoso, Siomar de Castro Soares,Aristóteles Góes-Neto,Wellington Francisco Rodrigues

Journal of fungi (Basel, Switzerland)（2025）

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phenetic analysis,metabolomics,clinical isolates,environmental isolates,antifungal resistance,virulence adaptation

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