KF1601, a Dual Inhibitor of BCR::ABL1 and FLT3, Overcomes Drug Resistance in FLT3+ Blast Phase Chronic Myeloid Leukemia

Hyun-Jin Kwon, Ji Eun Shin, Amir Khan, So Yeon Park, Jiyoung Kim, Jee-Young Lee, Doohyun Lee, Seungyeon Lee, Chun Young Im, Heegyum Moon, Ye Ri Han,Minori Tamai,Koshi Akahane,Takeshi Inukai,Wonhwa Lee, Hyelim Kim,Hong Nam Kim, Sung-Min Ahn,Hyun Woo Park,Dong-Wook Kim

Molecular Cancer（2025）

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关键词

KF1601,Chronic myeloid leukemia (CML),Chronic phase CML (CP-CML),Blast phase CML (BP-CML),Tyrosine kinase inhibitor (TKI),TKI resistance,FLT3,BCR::ABL1

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