There are five clear areas of focus for the translational research undertaken by the Gibbs Lab.

* We lead national and international cancer registries that capture comprehensive patient, tumour, treatment and outcome data for all major solid cancers. This data is used to enable audit and research, including supporting the novel concept of registry based clinical trials in oncology collection and translational research by combining data and tissue based research.

* More recently the Gibbs Lab have partnered with the Victorian Comprehensive Cancer Centre (VCCC) to undertake a number of registry-based trials. This work is ongoing with a number of new trial designs under review for inclusion as we expand the portfolio to different modalities of treatment of patients with cancer

* We lead multiple international randomised trials to define the potential of ctDNA as a marker of minimal residual disease to determine recurrence risk and to optimise adjuvant therapy.

* We have initiated studies of patient derived tumour organoids, with the ultimate aim of in vitro sensitivity testing being used to guide clinical treatment selection.

* Clinical Trials working with cooperative groups such as the AGITG and others to provide all aspects of clinical trial start up, initiation, study management to data analysis and close out.

Each program is led by a medical oncologist with appropriate sub-speciality expertise and substantial clinical appointments, with the ultimate focus being clinical relevance and impact.