Research Summary
1. Development of a clinically meaningful automated quantitative assessment of knee joint tissues volume
2. Significant Ankle Ligament Injury (SALI) cohort (PI)
Many patients following common severe ankle injury do not fully recover and end up with some lasting ankle problems that can limit the persons' lifestyle. The purpose of this study is to provide new knowledge about:
1) The type of people who attend ED suffering a significant ankle ligament injury 2) What it is about those people and their injury that may mean they go on to develop OA 3) What things influence this chance i.e. who is more likely and who is less likely to go on to develop OA after a significant ankle ligament injury
3. Understanding of clinically relevant phenotypes of osteoarthritis that can improve patient treatment and drug development.
4. The impact of Coronavirus (COVID-19) Infection on Recreational Runners: Risks, Recovery and Complications
Over the past forty years, running has developed into one of the most popular physical leisure activities in Europe. An estimated 50 million Europeans are engaged in running as a way to stay healthy and/or to challenge themselves and there has been a marked surge in running events all over Europe. Many active adults with coronavirus disease 2019 (COVID-19) experience prolonged fatigue and develop prolonged cardiac or respiratory symptoms during recovery period. It is anticipated that, with the increasing rate of infection in the general population, many participants will report a decline in running activities, followed by a recovery and return to training. Adequate understanding of the interplay between COVID-19 infection, training in running adults and early symptoms of poor recovery is required for creating of optimal recommendations and risk management of these patients. The short and medium-term adverse effects of COVID-19 infection on training capacity and cardiorespiratory complications are poorly understood.
OBJECTIVES: 1. to monitor the return to training following recovery from COVID 19 and the impact on subsequent physical activity, training performance and cardiorespiratory complications 2. to investigate the relationship between wellbeing, self-reported symptoms, heart rate variability, and subsequent participants illness/injury risk 3. to investigate the relationship between training load, wellbeing, and illness/injury risk 4. to perform subgroup analyses for sex, BMI, age groups, pre-existing health conditions, predominant type of exercise / running (eg. road, trail, fell, track,)