Guidelines for Clinical Evaluation of Chronic Kidney Disease in Early Stages

Clinical and Experimental Nephrology(2024)

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摘要
For the development of pharmaceutical products in kidney field, appropriate surrogate endpoints which can predict long-term prognosis are needed as an alternative to hard endpoints, such as end-stage kidney disease. Though international workshop has proposed estimated glomerular filtration rate (GFR) slope reduction of 0.5–1.0 mL/min/1.73 m /year and 30
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关键词
Chronic kidney disease,Diabetic kidney disease,Surrogate endpoint,eGFR slope,Albuminuria,Proteinuria
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