Guidelines for Clinical Evaluation of Chronic Kidney Disease in Early Stages
Clinical and Experimental Nephrology(2024)
摘要
For the development of pharmaceutical products in kidney field, appropriate surrogate endpoints which can predict long-term prognosis are needed as an alternative to hard endpoints, such as end-stage kidney disease. Though international workshop has proposed estimated glomerular filtration rate (GFR) slope reduction of 0.5–1.0 mL/min/1.73 m /year and 30
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关键词
Chronic kidney disease,Diabetic kidney disease,Surrogate endpoint,eGFR slope,Albuminuria,Proteinuria
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